Year: 2018 | Month: December | Volume 8 | Issue 6
Effect of Administration of Autologous Plasma along with Leucocytes on Hormonal Changes in Relation to Recovery Rate and Conception in Endometritic Cows
Abstract:
The effect of autologous plasma along with leucocytes in the treatment of endometritis and its relation with hormonal changes associated with recovery was evaluated in present study. A total of 16 endometritic crossbred cows were randomly allocated into two groups, Group I (n=10) received single intra uterine infusion of autologous plasma along with leucocytes whereas, the animals of Group II (n=6) served as control. Blood samples (5ml) were collected twice from all the experimental animals, first at the time of diagnosis of endometritis (pretreatment) and second at subsequent estrus (post-treatment). The clinical recovery was assessed by negative reaction in white side test and reduction of total bacterial count in cervico-vaginal mucus (CVM) at subsequent estrus and breeding was done through artificial insemination. Plasma thyroxin (T4), tri-iodo thyronine (T3) and cortisol concentration were evaluated in both the groups at pre and post treatment. Pregnancy was confirmed after 60 days post-insemination per rectally. The results revealed that plasma T3 (1.41±0.20 vs. 1.98±0.17 nM) and T4 concentration (27.11±5.97 vs. 35.98 ± 4.73 nM, p≤ 0.05) increased, whereas the cortisol level declined (6.77 ±1.38 vs. 2.12 ±0.63 ng/ml) following treatment with autologous plasma in the endometritic cows. The overall pregnancy rate was significantly higher in the treated group (70%) compared to no pregnancy in control. Thus, it can be concluded that treatment autologous plasma could be associated with restoration of thyroid hormones level and reduction of stress, besides improving the conception rate in the endometritic cows.
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